Human Chorionic Gonadotropin (HCG) Is Produced By The Cells Surrounding A Developing Embryo Known As Trophoblasts

Human Chorionic Gonadotropin (HCG)
Human Chorionic Gonadotropin (HCG)

The hormone known as Human Chorionic Gonadotropin (HCG) is produced by the trophoblast cells that surround a developing embryo (at first a syncytiotrophoblast), which after implantation develops into the placenta. Some pregnancy tests reveal the presence of hCG (HCG pregnancy strip tests). It is unknown if this production is a contributing cause or an outcome of carcinogenesis, but higher levels of this hormone tested in patients who are not pregnant may result in a cancer diagnosis and, if high enough, paraneoplastic syndromes. Pituitary glands of males and females of all ages generate luteinizing hormone (LH), the pituitary analogue of hCG.

The Human Chorionic Gonadotropin (HCG) Market is anticipated to reach US$ 710.88 million in 2022 and grow at a 6.5% CAGR during the forecast period.

There are numerous endogenous hCG variations. These various types' measurements are used to diagnose pregnancy and a number of different illness situations. Both conventional medicine and quackery have employed therapeutic uses for hCG preparations from a variety of sources. The selling of "homoeopathic" and over-the-counter hCG diet products has been outlawed by the US Food and Drug Administration as of December 6, 2011, and they have been deemed false and illegal.

A glycoprotein of 237 amino acids and a molecular mass of 36.7 kDa, Human Chorionic Gonadotropin (HCG) is roughly 14.5 kDa and 22.2 kDa. It has a (alpha) subunit that is the same as that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH), as well as a (beta) subunit that is specific to hCG. It is heterodimeric.

Human chorionic gonadotropin interacts with the ovarian LHCG receptor and encourages the preservation of the corpus luteum for the early pregnancy maternal detection. As a result, progesterone can be secreted during the first trimester by the corpus luteum. To support the developing foetus, progesterone gives the uterus a thick layer of blood vessels and capillaries.

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