Attapulgite is an Oral Drug Containing Magnesium Aluminum Phyllosilicate as a Base Mineral and is Commonly Consumed to Treat Diarrhea

Attapulgite
Attapulgite

Attapulgite, also known as Fullers Earth, is a soft clay mineral. It is a type of mineral that is highly absorbent and can be found in many natural and industrial products. It is widely used as a filler in paper, coatings, and in medicine. The crystals of actapulgite are needle-shaped, unlike bentonite, which is flake-like. It disperses readily in water and can thicken and suspend solutions.

Attapulgite is a clay mineral that is found in sedimentary rocks. It contains aluminum silicate. It can be used for various medical applications, from preventing diarrhea to improving gastrointestinal health. Its properties make it a valuable ingredient for the manufacturing of a wide range of pharmaceutical products. The clay is highly absorbent and helps increase water absorption. If it's not absorbed, actapulgite can help reduce water loss and help prevent diarrhea.

Studies using actapulgite have shown that it improves feed performance and health in piglets. Compared to a control diet that contained no clay, Attapulgite Market improved pellet hardness, microbial enterotoxins, and free-flowing properties. The study showed that actapulgite at various dilutions significantly increased the number of intestinal cells that survived in the piglets. The highest dilution of actapulgite produced an increase of 13% in surviving intestinal cells.

Using rat pulmonary alveolar macrophages, researchers tested actapulgite cytotoxic effects. The 250 ug of the mineral caused the same amount of cell damage in the animals, but the levels of effect were different. Palygorskite was more toxic than actapulgite, which was found to enhance alveolar macrophage cytotoxicity. However, the Working Group did not have any genetic data to determine the effectiveness of palygorskite.

Attapulgite is a magnesium-aluminum phyllosilicate that physically binds to toxins and bacteria in the digestive tract. Owing to this ability to adsorb toxins, it is used in many medications for diarrhea. It has been used as an antidiarrheal for decades. Many chemical companies in India supply actapulgite to the medical industry. For instance, in January 2022, Clariant AG announced the purchase of BASF’s actapulgite business assets at the Quincy mining facility in Florida, U.S., at a valuation of US$ 60 million to broaden its North American footprint.

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