Anatomic Pathology Refers to the Examination of Organs and Tissues Utilizing Both Microscopic and Biochemical Methods for Diagnosis

Anatomic Pathology
Anatomic Pathology

Anatomic Pathology entails the direct observation of human tissue under a microscope and as a gross examination for the appropriate diagnosis of a disease or pathological condition. Surgical pathology, oral and maxillofacial pathology, cytopathology, molecular pathology, and forensic pathology are all subtypes of pathology. Gross inspection, histopathology, immunohistochemistry, in situ hybridization, cytopathology, tissue cytogenetics, and other procedures are conducted in pathology. Microscopic examination of tissue samples with the aid of one or more stains is the standard approach in anatomical pathology. Stains have been produced by manufacturers to identify and classify bacteria in tissue samples or excisional specimens. In tissue samples, several gram stains and acid-fast stains can be used to detect bacteria and mycobacteria.

Immunohistochemistry is the imaging of antigens in cells of a tissue segment in order to determine the tissue distribution of a disease-causing antigen. Immunohistochemistry is commonly used in cancer diagnostics to identify tumor antigens that are produced in a specific way. CryoStar NX70 Cryostat, ClearVue Coverslipper, and Shandon Cytoblock cell block preparation system, Excelsior AS Tissue Processor, and ultraView SISH DNP are examples of commercially accessible Anatomic Pathology products. Tissue processing systems, microtomes, cryostats, and immunohistochemistry products are among the commercially available items, as are accessories such as cytology and microtome accessories. 

Microtomes are used to cut tissue blocks with precision, control, and comfort at room temperature. They can be operated manually, semi-automatic, or fully automated. Cryostats, on the other hand, are used to cut frozen tissue blocks into parts at subzero temperatures. The Anatomic Pathology market has grown as a result of new product introductions and increased mergers and acquisitions. For example, in June 2018, PHC Holdings Corporation finalized the acquisition of Thermo Fisher Scientific Inc.'s Anatomical Pathology division. The acquired Anatomical Pathology business will become Epredia, a new stand-alone company that will be a leading global provider of comprehensive anatomical pathology solutions.

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